https://doi.org/10.4081/uij.2022.283
A retrospective analysis of 47 procedures using a bioresorbable polycaprolactone based injectable for the treatment of mild to moderate stress urinary incontinence in adult females
Submitted: 3 January 2022
Accepted: 23 May 2022
Published: 10 June 2022
Accepted: 23 May 2022
Abstract Views: 1230
PDF: 355
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Over the recent years, potential longterm complications of permanent implants for urinary incontinence has become a topic of debate. As a result there is an increasing interest in less invasive and bioresorbable procedures from both healthcare professional as well as patients that ideally can be performed in an out-patient setting. This brief report describes our initial results using a novel bioresorbable injectable product for the treatment of female mild to moderate stress urinary incontinence. The results show that the majority of patients respond well to treatment and remain continent for the initial 12 months following injection. Complication rate is low and consisted of mild and transient events. These initial results are promising and merit further investigation into using this procedure as first-choice after unsuccessful conservative treatments such as pelvic floor muscle therapy.
Lukacz ES, Santiago-Lastra Y, Albo ME, et al. Urinary incontinence in women: A review. JAMA 2017;318:1592-604.
DOI: https://doi.org/10.1001/jama.2017.12137
Rovner ES, and Wein AJ. Treatment options for stress urinary incontinence. Rev Urol 2004;6:S29-47.
Blaivas JG, Purohit RS, Benedon MS, et al. Safety considerations for synthetic sling surgery. Nat Rev Urol 2015;12:481-509.
DOI: https://doi.org/10.1038/nrurol.2015.183
Dwyer L, Weaver E, Rajai A, et al. “Voice your choice”: a study of women’s choice of surgery for primary stress urinary incontinence. Int Urygynecol J 2020;31:769-77.
DOI: https://doi.org/10.1007/s00192-019-04202-6
Ong HL, Sokolova I, Bekarma H, et al. Development, validation and initial evaluation of patient-decision aid (SUI-PDA©) for women considering stress urinary incontinence surgery. Int Urogyn J 2019;30:2013-2022.
DOI: https://doi.org/10.1007/s00192-019-04047-z
Robinson D, Anders K, Cardozo L, et al. What women want – their interpretation of the concept of cure. J Pelvic Med Surg 2003;9:273-77.
DOI: https://doi.org/10.1097/01.spv.0000095060.05452.3f
Stamey TA. Endoscopic suspension of the vesical neck for urinary incontinence in females. Ann Surg 1980;192:465–71.
DOI: https://doi.org/10.1097/00000658-198010000-00005
Ghoniem G, Stanford E, Kenton K, et al. Evaluation and outcome measures in the treatment of female urinary stress incontinence: International Urogynecological Association (IUGA) guidelines for research and clinical practice. Int Urogynecol J Pelvic Floor Dysfunct 2008;19:5-33.
DOI: https://doi.org/10.1007/s00192-007-0495-5
Kastelein AW, Dicker MFA, Opmeer BC, et al. Innovative treatment modalities for urinary incontinence: a European survey identifying experience and attitude of healthcare providers. Int Urogynecol J 2017;28:1725-31.
DOI: https://doi.org/10.1007/s00192-017-3339-y
Koldewijn EL, Oerlemans DJAJ, Beulens A, et al. Treatment of Mild to Moderate Stress Urinary Incontinence with a Novel Polycaprolactone-Based Bioresorbable Urethral Bulking Agent. Urogynaecologia Int J 2022;34:287.
DOI: https://doi.org/10.4081/uij.2022.287
How to Cite
Mojsović, A., & Koldewijn, E. (2022). A retrospective analysis of 47 procedures using a bioresorbable polycaprolactone based injectable for the treatment of mild to moderate stress urinary incontinence in adult females. Urogynaecologia, 34(1). https://doi.org/10.4081/uij.2022.283
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